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KMID : 0604520190450020209
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Journal of the Society of Cosmetic Scientists of Korea
2019 Volume.45 No. 2 p.209 ~ p.216
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Photoprotective Effects of Silybum marianum Extract
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Kim Dae-Hyun
Bae Woo-Ri
Kim Yun-Sun
Shin Dong-Won
Park Sun-Gyoo
Kang Nae-Gyu
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Abstract
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Ultraviolet rays (UV) cause photoaging by inducing skin photodamages such as erythema and sunburn. Silymarin is a mixture of antioxidant polyphenols extracted from Silybum marianum fruit (S. m), which is known as milk thistle.
It is known to protect skin tissues from UV treatment and antioxidant effects. In this study, we aimed to identify the photoprotective effects of S. m extract, which has silymarin in the epidermis layer of the skin. We found that the extract can function as a UV filter, so it can reduce DNA damage by UV treatment. Especially, we found that, in the stratum corneum, the extract can suppress the protein carbonylarion and DNA damages caused by suberythemal dose of UV treatment which does not induce erythema in the skin. UV treatment also increased protein carbonylation levels in the stratum corneum by oxidation, but it was prevented by applying the extract. The extract can absorb UV with minimal phototoxicity. Together, our study suggests that S. m extract can be used as a photo-protective ingredient to avoid photoaging of the skin.
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KEYWORD
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Silybum marianum extract, photoprotection, DNA damage, protein carbonylation
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